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TitleInsights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 110, Page 14634-14639, Year 2013
Publish dateAug 7, 2013 (structure data deposition date)
AuthorsXu, K. / Tzvetkova-Robev, D. / Xu, Y. / Goldgur, Y. / Chan, Y.P. / Himanen, J.P. / Nikolov, D.B.
External linksProc. Natl. Acad. Sci. USA / PubMed:23959867
MethodsX-ray diffraction
Resolution2.081 - 3.13 Å
Structure data

PDB-4m4p:
Crystal structure of EPHA4 ectodomain
Method: X-RAY DIFFRACTION / Resolution: 2.081 Å

PDB-4m4r:
Epha4 ectodomain complex with ephrin a5
Method: X-RAY DIFFRACTION / Resolution: 3.13 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / eph receptor protein kinase / eph receptor ephrin complex

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