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TitleInsight into mechanisms of 3'-5' exonuclease activity and removal of bulky 8,5'-cyclopurine adducts by apurinic/apyrimidinic endonucleases.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 110, Page E3071-E3080, Year 2013
Publish dateApr 5, 2013 (structure data deposition date)
AuthorsMazouzi, A. / Vigouroux, A. / Aikeshev, B. / Brooks, P.J. / Saparbaev, M.K. / Morera, S. / Ishchenko, A.A.
External linksProc. Natl. Acad. Sci. USA / PubMed:23898172
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-4k1g:
Structure of E. coli Nfo(Endo IV)-H69A mutant bound to a cleaved DNA duplex containing a alphadA:T basepair
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsHYDROLASE/DNA / DNA endonuclease IV / HYDROLASE-DNA complex

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