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Structure paper

TitleA switch III motif relays signaling between a B12 enzyme and its G-protein chaperone.
Journal, issue, pagesNat. Chem. Biol., Vol. 9, Page 535-539, Year 2013
Publish dateMar 29, 2013 (structure data deposition date)
AuthorsLofgren, M. / Padovani, D. / Koutmos, M. / Banerjee, R.
External linksNat. Chem. Biol. / PubMed:23873214
MethodsX-ray diffraction
Resolution2.1 - 2.2 Å
Structure data

PDB-4jyb:
MeaB, A Bacterial Homolog of MMAA, Bound to GMPPNP
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-4jyc:
MeaB, A Bacterial Homolog of MMAA, in its Apo form
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-GNP:
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER / GppNHp, GMPPNP, energy-carrying molecule analogue*YM

ChemComp-HOH:
WATER

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

Source
  • methylobacterium extorquens (bacteria)
KeywordsHYDROLASE / Alpha and beta protein / P-loop containing nucleoside triphosphate hydrolases / GTPase / Metallochaperone / Methylmalonyl-CoA Mutase (MCM) / CHAPERONE

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