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TitleAutoinhibition and Phosphorylation-Induced Activation of Phospholipase C-gamma Isozymes.
Journal, issue, pagesBiochemistry, Vol. 52, Page 4810-4819, Year 2013
Publish dateApr 11, 2013 (structure data deposition date)
AuthorsHajicek, N. / Charpentier, T.H. / Rush, J.R. / Harden, T.K. / Sondek, J.
External linksBiochemistry / PubMed:23777354
MethodsX-ray diffraction
Resolution1.5 - 1.7 Å
Structure data

PDB-4k44:
Auto-inhibition and phosphorylation-induced activation of PLC-gamma isozymes
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-4k45:
Auto-inhibition and phosphorylation-induced activation of PLC-gamma isozymes
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • rattus norvegicus (Norway rat)
KeywordsHYDROLASE / SH2 domain / PLC-gamma1 / HYDROLASE/HYDROLASE INHIBITOR / HYDROLASE-HYDROLASE INHIBITOR complex

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