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Structure paper

TitleProgressive multifocal leukoencephalopathy-associated mutations in the JC polyomavirus capsid disrupt lactoseries tetrasaccharide c binding.
Journal, issue, pagesMBio, Vol. 4, Page e00247-e00213, Year 2013
Publish dateFeb 21, 2013 (structure data deposition date)
AuthorsMaginnis, M.S. / Stroh, L.J. / Gee, G.V. / O'Hara, B.A. / Derdowski, A. / Stehle, T. / Atwood, W.J.
External linksMBio / PubMed:23760462
MethodsX-ray diffraction
Resolution1.9 - 2.2 Å
Structure data

PDB-4jcd:
S268Y Variant of JC Polyomavirus Major Capsid Protein VP1
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-4jce:
L54F Variant of JC Polyomavirus Major Capsid Protein VP1
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-4jcf:
S268F Variant of JC Polyomavirus Major Capsid Protein VP1 in Complex with LSTc
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • jc polyomavirus
KeywordsVIRAL PROTEIN / beta-sandwich / jelly roll topology / major capsid protein / PML-associated VP1 mutation / LSTc receptor motif

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