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Structure paper

TitleProtein conformational change delayed by steric hindrance from an N-linked glycan.
Journal, issue, pagesJ. Mol. Biol., Vol. 425, Page 2867-2877, Year 2013
Publish dateFeb 21, 2012 (structure data deposition date)
AuthorsBager, R. / Johansen, J.S. / Jensen, J.K. / Stensballe, A. / Jendroszek, A. / Buxbom, L. / Sorensen, H.P. / Andreasen, P.A.
External linksJ. Mol. Biol. / PubMed:23702291
MethodsX-ray diffraction
Resolution1.6682 - 1.96 Å
Structure data

PDB-4dte:
Crystal structure of zebrafish plasminogen activator inhibitor-1 (PAI-1)
Method: X-RAY DIFFRACTION / Resolution: 1.96 Å

PDB-4kds:
Crystal structure of latent rainbow trout plasminogen activator inhibitor 1 (PAI-1)
Method: X-RAY DIFFRACTION / Resolution: 1.6682 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • danio rerio (zebrafish)
  • oncorhynchus mykiss (rainbow trout)
KeywordsHYDROLASE INHIBITOR / Active serpin / zebarfish uPA / Serpin / Inactive serpin / trout uPA

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