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TitleStructural and Pharmacological Characterization of Novel Potent and Selective Monoclonal Antibody Antagonists of Glucose-dependent Insulinotropic Polypeptide Receptor.
Journal, issue, pagesJ. Biol. Chem., Vol. 288, Page 19760-19772, Year 2013
Publish dateOct 12, 2012 (structure data deposition date)
AuthorsRavn, P. / Madhurantakam, C. / Kunze, S. / Matthews, E. / Priest, C. / O'Brien, S. / Collinson, A. / Papworth, M. / Fritsch-Fredin, M. / Jermutus, L. ...Ravn, P. / Madhurantakam, C. / Kunze, S. / Matthews, E. / Priest, C. / O'Brien, S. / Collinson, A. / Papworth, M. / Fritsch-Fredin, M. / Jermutus, L. / Benthem, L. / Gruetter, M. / Jackson, R.H.
External linksJ. Biol. Chem. / PubMed:23689510
MethodsX-ray diffraction
Resolution3 Å
Structure data

PDB-4hj0:
Crystal structure of the human GIPr ECD in complex with Gipg013 Fab at 3-A resolution
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Glucagon receptor sub-family recognition fold

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