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Structure paper

TitleControl of DNA minor groove width and Fis protein binding by the purine 2-amino group.
Journal, issue, pagesNucleic Acids Res., Vol. 41, Page 6750-6760, Year 2013
Publish dateDec 19, 2012 (structure data deposition date)
AuthorsHancock, S.P. / Ghane, T. / Cascio, D. / Rohs, R. / Di Felice, R. / Johnson, R.C.
External linksNucleic Acids Res. / PubMed:23661683
MethodsX-ray diffraction
Resolution2.7 - 2.9 Å
Structure data

PDB-4ihv:
Crystal structure of Fis bound to 27 bp sequence DNA F28 (AAATTTGTTTGAGCGTTGAGCAAATTT)
Method: X-RAY DIFFRACTION / Resolution: 2.716 Å

PDB-4ihw:
Crystal structure of Fis bound to 27 bp Inosine substituted DNA F28-dI (AAATTTGTTTGAICITTGAGCAAATTT)
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-4ihx:
Crystal structure of Fis bound to 27 bp 2-Aminopurine substituted DNA F28-2AP (AAATTTGTTTGA2T2TTGAGCAAATTT)
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-4ihy:
Crystal structure of Fis bound to 27bp Inosine substituted DNA F29-dI (AAATTTGTTTGIICICTGAGCAAATTT)
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsTRANSCRIPTION/DNA / Protein-DNA complex / HTH domain / minor groove compression / DNA bending / indirect recognition / TRANSCRIPTION-DNA complex

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