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TitleStructure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody.
Journal, issue, pagesScience, Vol. 340, Page 1113-1117, Year 2013
Publish dateMar 4, 2013 (structure data deposition date)
AuthorsMcLellan, J.S. / Chen, M. / Leung, S. / Graepel, K.W. / Du, X. / Yang, Y. / Zhou, T. / Baxa, U. / Yasuda, E. / Beaumont, T. ...McLellan, J.S. / Chen, M. / Leung, S. / Graepel, K.W. / Du, X. / Yang, Y. / Zhou, T. / Baxa, U. / Yasuda, E. / Beaumont, T. / Kumar, A. / Modjarrad, K. / Zheng, Z. / Zhao, M. / Xia, N. / Kwong, P.D. / Graham, B.S.
External linksScience / PubMed:23618766
MethodsX-ray diffraction
Resolution1.6 - 3.6 Å
Structure data

PDB-4jha:
Crystal Structure of RSV-Neutralizing Human Antibody D25
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-4jhw:
Crystal Structure of Respiratory Syncytial Virus Fusion Glycoprotein Stabilized in the Prefusion Conformation by Human Antibody D25
Method: X-RAY DIFFRACTION / Resolution: 3.6 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • human respiratory syncytial virus
KeywordsIMMUNE SYSTEM / Immunoglobulin / Ig / immunoglobulin; type I fusion protein / membrane fusion

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