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-Structure paper
Title | Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases. |
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Journal, issue, pages | J. Med. Chem., Vol. 56, Page 3768-3782, Year 2013 |
Publish date | Feb 15, 2011 (structure data deposition date) |
![]() | Schonbrunn, E. / Betzi, S. / Alam, R. / Martin, M.P. / Becker, A. / Han, H. / Francis, R. / Chakrasali, R. / Jakkaraj, S. / Kazi, A. ...Schonbrunn, E. / Betzi, S. / Alam, R. / Martin, M.P. / Becker, A. / Han, H. / Francis, R. / Chakrasali, R. / Jakkaraj, S. / Kazi, A. / Sebti, S.M. / Cubitt, C.L. / Gebhard, A.W. / Hazlehurst, L.A. / Tash, J.S. / Georg, G.I. |
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Methods | X-ray diffraction |
Resolution | 1.42 - 2.1 Å |
Structure data | ![]() PDB-3qqk: ![]() PDB-3qtq: ![]() PDB-3qtr: ![]() PDB-3qts: ![]() PDB-3qtu: ![]() PDB-3qtw: ![]() PDB-3qtx: ![]() PDB-3qtz: ![]() PDB-3qu0: ![]() PDB-3qxp: ![]() PDB-3r8u: ![]() PDB-3r8v: ![]() PDB-3r8z: ![]() PDB-3r9d: ![]() PDB-3r9h: ![]() PDB-3r9n: ![]() PDB-3r9o: ![]() PDB-3rah: ![]() PDB-3rak: ![]() PDB-3ral: ![]() PDB-3rjc: ![]() PDB-3rk5: ![]() PDB-3rk7: ![]() PDB-3rk9: ![]() PDB-3rkb: ![]() PDB-3rmf: ![]() PDB-3rni: ![]() PDB-3rpr: ![]() PDB-3rpv: ![]() PDB-3rpy: ![]() PDB-3rzb: ![]() PDB-3s00: ![]() PDB-3s0o: ![]() PDB-3s1h: ![]() PDB-3sqq: ![]() PDB-4gcj: |
Chemicals | ![]() ChemComp-EDO: ![]() ChemComp-X02: ![]() ChemComp-HOH: ![]() ChemComp-X35: ![]() ChemComp-X36: ![]() ChemComp-X46: ![]() ChemComp-X44: ![]() ChemComp-X3A: ![]() ChemComp-X43: ![]() ChemComp-X42: ![]() ChemComp-X40: ![]() ChemComp-X64: ![]() ChemComp-Z31: ![]() ChemComp-Z62: ![]() ChemComp-Z63: ![]() ChemComp-X6B: ![]() ChemComp-Z67: ![]() ChemComp-Z68: ![]() ChemComp-Z71: ![]() ChemComp-O1Z: ![]() ChemComp-03Z: ![]() ChemComp-04Z: ![]() ChemComp-06Z: ![]() ChemComp-07Z: ![]() ChemComp-08Z: ![]() ChemComp-09Z: ![]() ChemComp-12Z: ![]() ChemComp-20Z: ![]() ChemComp-21Z: ![]() ChemComp-25Z: ![]() ChemComp-26Z: ![]() ChemComp-27Z: ![]() ChemComp-02Z: ![]() ChemComp-Z60: ![]() ChemComp-50Z: ![]() ChemComp-56Z: ![]() ChemComp-99Z: |
Source |
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![]() | TRANSFERASE/TRANSFERASE INHIBITOR / protein kinase / inhibitor / TRANSFERASE-TRANSFERASE INHIBITOR complex |