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TitleHeteroresistance to Fosfomycin is Predominant in Streptococcus Pneumoniae and Depends on Mura1 Gene.
Journal, issue, pagesAntimicrob. Agents Chemother., Vol. 57, Page 2801-, Year 2013
Publish dateDec 20, 2012 (structure data deposition date)
AuthorsEngel, H. / Gutierrez-Fernandez, J. / Fluckiger, C. / Martinez-Ripoll, M. / Muhlemann, K. / Hermoso, J.A. / Hilty, M. / Hathaway, L.J.
External linksAntimicrob. Agents Chemother. / PubMed:23571543
MethodsX-ray diffraction
Resolution1.8 - 2.9 Å
Structure data

PDB-3zh3:
crystal structure of S. pneumoniae D39 native MurA1
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-3zh4:
crystal structure of S. pneumoniae Hungary 19A MurA1 in complex with citrate
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-FLC:
CITRATE ANION

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

Source
  • streptococcus pneumoniae (bacteria)
KeywordsTRANSFERASE / ENOLPYRUVYL TRANSFERASE / MURA

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