EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Crystallization of bi-functional ligand protein complexes.
ジャーナル・号・ページ	J. Struct. Biol., Vol. 182, Page 246-254, Year 2013
掲載日	2012年9月11日 (構造データの登録日)
著者	Antoni, C. / Vera, L. / Devel, L. / Catalani, M.P. / Czarny, B. / Cassar-Lajeunesse, E. / Nuti, E. / Rossello, A. / Dive, V. / Stura, E.A.
リンク	J. Struct. Biol. / PubMed:23567804
手法	X線回折
解像度	1.43 - 2.902 Å
構造データ	PDB-4h1q: Crystal structure of mutant MMP-9 catalytic domain in complex with a twin inhibitor. 手法: X-RAY DIFFRACTION / 解像度: 1.59 Å PDB-4h2e: Crystal structure of an MMP twin inhibitor complexing two MMP-9 catalytic domains 手法: X-RAY DIFFRACTION / 解像度: 2.902 Å PDB-4h30: Crystal structure of the catalytic domain of MMP-12 in complex with a twin inhibitor. 手法: X-RAY DIFFRACTION / 解像度: 1.43 Å PDB-4h3x: Crystal structure of an MMP broad spectrum hydroxamate based inhibitor CC27 in complex with the MMP-9 catalytic domain 手法: X-RAY DIFFRACTION / 解像度: 1.764 Å PDB-4h49: Crystal structure of the catalytic domain of MMP-12 in complex with a twin inhibitor. 手法: X-RAY DIFFRACTION / 解像度: 2.16 Å PDB-4h76: Crystal structure of the catalytic domain of Human MMP12 in complex with a broad spectrum hydroxamate inhibitor 手法: X-RAY DIFFRACTION / 解像度: 1.5 Å PDB-4h82: Crystal structure of mutant MMP-9 catalytic domain in complex with a twin inhibitor. 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-4h84: Crystal structure of the catalytic domain of Human MMP12 in complex with a selective carboxylate based inhibitor. 手法: X-RAY DIFFRACTION / 解像度: 1.592 Å PDB-4hma: Crystal structure of an MMP twin carboxylate based inhibitor LC20 in complex with the MMP-9 catalytic domain 手法: X-RAY DIFFRACTION / 解像度: 1.94 Å PDB-4i03: Human MMP12 in complex with a PEG-linked bifunctional L-glutamate motif inhibitor 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å
化合物	ChemComp-ZN: Unknown entry ChemComp-CA: Unknown entry / カルシウムジカチオン ChemComp-0XX: N-(4-{[(3R)-3-[(biphenyl-4-ylsulfonyl)(propan-2-yloxy)amino]-4-(hydroxyamino)-4-oxobutyl]amino}-4-oxobutyl)-N'-(4-{[(3S)-3-[(biphenyl-4-ylsulfonyl)(propan-2-yloxy)amino]-4-(hydroxyamino)-4-oxobutyl]amino}-4-oxobutyl)benzene-1,3-dicarboxamide ChemComp-HOH: WATER ChemComp-PEG: DI(HYDROXYETHYL)ETHER / ジエチレングリコ-ル ChemComp-ACT: ACETATE ION / 酢酸イオン ChemComp-BCN: BICINE / N,N-ビス(2-ヒドロキシエチル)グリシン / pH緩衝剤YM ChemComp-0Y3: N,N'-bis(4-{[(3R)-3-[(biphenyl-4-ylsulfonyl)(propan-2-yloxy)amino]-4-(hydroxyamino)-4-oxobutyl]amino}-4-oxobutyl)benzene-1,3-dicarboxamide ChemComp-GOL: GLYCEROL / グリセロ-ル ChemComp-0ZD: N,N'-bis(2-[(biphenyl-4ylsulfonyl)[(2R)-1-hydroxy-3-methyl-1-oxobutan-2-yl]-amino]ethyl)benzene-1,3-dicarboxamide ChemComp-10B: N-2-(biphenyl-4-ylsulfonyl)-N-2-(isopropyloxy)-acetohydroxamic acid ChemComp-PGO: S-1,2-PROPANEDIOL / (S)-1,2-プロパンジオ-ル ChemComp-DMS: DIMETHYL SULFOXIDE / 2-チアプロパン2-オキシド / DMSO, 沈殿剤YM ChemComp-L29: N,N'-bis(2-{(biphenyl-4-ylsulfonyl)[(2R)-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]amino}ethyl)benzene-1,3-dicarboxamide (non-preferred name) ChemComp-PPI: PROPANOIC ACID / プロピオン酸 ChemComp-Y38: N-[2-(benzoylamino)ethyl]-N-(biphenyl-4-ylsulfonyl)-D-valine ChemComp-PGR: R-1,2-PROPANEDIOL / (R)-1,2-プロパンジオ-ル ChemComp-MLT: D-MALATE / D-りんご酸 ChemComp-L88: (4R,22R)-5,21-dioxo-4,22-bis({3-[4-(4-phenylthiophen-2-yl)phenyl]propanoyl}amino)-10,13,16-trioxa-6,20-diazapentacosane-1,25-dioic acid ChemComp-EDO: 1,2-ETHANEDIOL / エチレングリコ-ル
由来	homo sapiens (ヒト)
キーワード	HYDROLASE/HYDROLASE inhibitor / HYDROLASE/TWIN INHIBITOR / Zincin-like / Gelatinase / Collagenase (Catalytic Domain) / HYDROLASE-HYDROLASE inhibitor complex / divalent inhibitor / carboxylic twin inhibitor / Dimerisation / METZINCIN / Zinc protease / hydrolase-hydrolase inhibtior complex / HYDROLASE/HYDROXAMATE INHIBITOR / Broad spectrum MMP hydroxamate inhibitor / selective carboxylate based MMP-12 inhibitor / selective carboxylate based MMP-12 bifunctional inhibitor