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Structure paper

TitleStructure of the Absent in Melanoma 2 (AIM2) Pyrin Domain Provides Insights into the Mechanisms of AIM2 Autoinhibition and Inflammasome Assembly.
Journal, issue, pagesJ. Biol. Chem., Vol. 288, Page 13225-13235, Year 2013
Publish dateJan 4, 2012 (structure data deposition date)
AuthorsJin, T. / Perry, A. / Smith, P. / Jiang, J. / Xiao, T.S.
External linksJ. Biol. Chem. / PubMed:23530044
MethodsX-ray diffraction
Resolution2.0685 Å
Structure data

PDB-3vd8:
Crystal structure of human AIM2 PYD domain with MBP fusion
Method: X-RAY DIFFRACTION / Resolution: 2.0685 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-K:
Unknown entry

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
  • homo sapiens (human)
KeywordsSUGAR BINDING PROTEIN / SIGNALING PROTEIN / MBP/PYD/DD / signal transduction / inflammasome

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