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TitleThe human ITPA polymorphic variant P32T is destabilized by the unpacking of the hydrophobic core.
Journal, issue, pagesJ. Struct. Biol., Vol. 182, Page 197-208, Year 2013
Publish dateMay 18, 2012 (structure data deposition date)
AuthorsSimone, P.D. / Struble, L.R. / Kellezi, A. / Brown, C.A. / Grabow, C.E. / Khutsishvili, I. / Marky, L.A. / Pavlov, Y.I. / Borgstahl, G.E.
External linksJ. Struct. Biol. / PubMed:23528839
MethodsX-ray diffraction
Resolution2.07 Å
Structure data

PDB-4f95:
Crystal structure of human inosine triphosphate pyrophosphatase P32T variant
Method: X-RAY DIFFRACTION / Resolution: 2.07 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE

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