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Structure paper

TitleStructural characterization of V57D and V57P mutants of human cystatin C, an amyloidogenic protein.
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 69, Page 577-586, Year 2013
Publish dateMay 25, 2011 (structure data deposition date)
AuthorsOrlikowska, M. / Szymanska, A. / Borek, D. / Otwinowski, Z. / Skowron, P. / Jankowska, E.
External linksActa Crystallogr. ,Sect. D / PubMed:23519666
MethodsX-ray diffraction
Resolution2.26 - 3.02 Å
Structure data

PDB-3s67:
Crystal structure of V57P mutant of human cystatin C
Method: X-RAY DIFFRACTION / Resolution: 2.26 Å

PDB-3sva:
Crystal structure of V57D mutant of human cystatin C
Method: X-RAY DIFFRACTION / Resolution: 3.02 Å

Chemicals

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-IMD:
IMIDAZOLE

ChemComp-ACT:
ACETATE ION

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE INHIBITOR / 3D domain swapping / cysteine protease inhibitor

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