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Structure paper

TitlePreemptive priming readily overcomes structure-based mechanisms of virus escape.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 110, Page 5570-5575, Year 2013
Publish dateNov 4, 2012 (structure data deposition date)
AuthorsValkenburg, S.A. / Gras, S. / Guillonneau, C. / Hatton, L.A. / Bird, N.A. / Twist, K.A. / Halim, H. / Jackson, D.C. / Purcell, A.W. / Turner, S.J. ...Valkenburg, S.A. / Gras, S. / Guillonneau, C. / Hatton, L.A. / Bird, N.A. / Twist, K.A. / Halim, H. / Jackson, D.C. / Purcell, A.W. / Turner, S.J. / Doherty, P.C. / Rossjohn, J. / Kedzierska, K.
External linksProc. Natl. Acad. Sci. USA / PubMed:23493558
MethodsX-ray diffraction
Resolution2 - 3.16 Å
Structure data

PDB-4huu:
Crystal Structure of H2Db-NPM6I
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-4huv:
Crystal Structure of H2Db-NPM6W
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-4huw:
Crystal Structure of H2Db-NPM6T
Method: X-RAY DIFFRACTION / Resolution: 3.16 Å

PDB-4hux:
Crystal Structure of H2Db-H155A-NP
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-4hv8:
Crystal Structure of H2Db-H155A-NPM6I
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

Source
  • mus musculus (house mouse)
  • synthetic construct (others)
KeywordsIMMUNE SYSTEM / viral immunity / T cell / H2Db / influenza / viral escape

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