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Structure paper

TitleCrystal structures of the calcium pump and sarcolipin in the Mg2+-bound E1 state.
Journal, issue, pagesNature, Vol. 495, Page 260-264, Year 2013
Publish dateJan 27, 2013 (structure data deposition date)
AuthorsToyoshima, C. / Iwasawa, S. / Ogawa, H. / Hirata, A. / Tsueda, J. / Inesi, G.
External linksNature / PubMed:23455422
MethodsX-ray diffraction
Resolution2.45 - 3.2 Å
Structure data

PDB-3w5a:
Crystal structure of the calcium pump and sarcolipin from rabbit fast twitch skeletal muscle in the E1.Mg2+ state
Method: X-RAY DIFFRACTION / Resolution: 3.01 Å

PDB-3w5b:
Crystal structure of the recombinant SERCA1a (calcium pump of fast twitch skeletal muscle) in the E1.Mg2+ state
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-3w5c:
Crystal structure of the calcium pump in the E2 state free from exogenous inhibitors
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-3w5d:
Crystal structure of the calcium pump in the E2+Pi state
Method: X-RAY DIFFRACTION / Resolution: 2.45 Å

Chemicals

ChemComp-TM1:
2',3'-O-[(1r)-2,4,6-trinitrocyclohexa-2,5-diene-1,1-diyl]adenosine 5'-(dihydrogen phosphate)

ChemComp-PTY:
PHOSPHATIDYLETHANOLAMINE / phospholipid*YM

ChemComp-MG:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • oryctolagus cuniculus (rabbit)
KeywordsMETAL TRANSPORT/MEMBRANE PROTEIN / P-TYPE ATPASE / HYDROLASE / CALCIUM TRANSPORT / CALCIUM BINDING / ATP BINDING / ENDOPLASMIC RETICULUM / SARCOLIPIN / METAL TRANSPORT-MEMBRANE PROTEIN complex / METAL TRANSPORT / SARCOPLASMIC RETICULUM / RECOMBINANT

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