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TitleThe crystal structure of the DNA-binding domain of vIRF-1 from the oncogenic KSHV reveals a conserved fold for DNA binding and reinforces its role as a transcription factor.
Journal, issue, pagesNucleic Acids Res., Vol. 41, Page 4295-4306, Year 2013
Publish dateOct 17, 2012 (structure data deposition date)
AuthorsHew, K. / Dahlroth, S.L. / Venkatachalam, R. / Nasertorabi, F. / Lim, B.T. / Cornvik, T. / Nordlund, P.
External linksNucleic Acids Res. / PubMed:23435230
MethodsX-ray diffraction
Resolution1.48 - 2.379 Å
Structure data

PDB-4hlx:
The crystal structure of the DNA binding domain of vIRF-1 from the oncogenic KSHV
Method: X-RAY DIFFRACTION / Resolution: 2.379 Å

PDB-4hly:
The complex crystal structure of the DNA binding domain of vIRF-1 from the oncogenic KSHV with DNA
Method: X-RAY DIFFRACTION / Resolution: 1.48 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • human herpesvirus 8
  • synthetic construct (others)
KeywordsDNA BINDING PROTEIN / helix-turn-helix / DNA BINDING PROTEIN/DNA / DNA BINDING PROTEIN-DNA complex

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