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Structure paper

TitleStructure of the Bifunctional Acyltransferase/Decarboxylase LnmK from the Leinamycin Biosynthetic Pathway Revealing Novel Activity for a Double-Hot-Dog Fold.
Journal, issue, pagesBiochemistry, Vol. 52, Page 902-911, Year 2013
Publish dateNov 15, 2012 (structure data deposition date)
AuthorsLohman, J.R. / Bingman, C.A. / Phillips, G.N. / Shen, B.
External linksBiochemistry / PubMed:23320975
MethodsX-ray diffraction
Resolution1.76 - 2.25 Å
Structure data

PDB-4hzn:
The Structure of the Bifunctional Acetyltransferase/Decarboxylase LnmK from the Leinamycin Biosynthetic Pathway Revealing Novel Activity for a Double Hot Dog Fold
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-4hzo:
The Structure of the Bifunctional Acetyltransferase/Decarboxylase LnmK from the Leinamycin Biosynthetic Pathway Revealing Novel Activity for a Double Hot Dog Fold
Method: X-RAY DIFFRACTION / Resolution: 1.76 Å

PDB-4hzp:
The Structure of the Bifunctional Acetyltransferase/Decarboxylase LnmK from the Leinamycin Biosynthetic Pathway Revealing Novel Activity for a Double Hot Dog Fold
Method: X-RAY DIFFRACTION / Resolution: 1.77 Å

Chemicals

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-CL:
Unknown entry

ChemComp-COA:
COENZYME A

Source
  • streptomyces atroolivaceus (bacteria)
KeywordsTRANSFERASE / Structural Genomics / Protein Structure Initiative / Enzyme Discovery for Natural Product Biosynthesis / NatPro / PSI-Biology / Double Hot Dog Fold / Bifunctional methylmalonyl-CoA:ACP Acyltransferase/Decarboxylase / Acyl Carrier Protein (LnmK) methylmalonyl-CoA / LYASE / Acyl Carrier Protein - LnmL / methylmalonyl-CoA

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