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Structure paper

TitleMechanism for KRIT1 Release of ICAP1-Mediated Suppression of Integrin Activation.
Journal, issue, pagesMol. Cell, Vol. 49, Page 719-729, Year 2013
Publish dateFeb 27, 2012 (structure data deposition date)
AuthorsLiu, W. / Draheim, K.M. / Zhang, R. / Calderwood, D.A. / Boggon, T.J.
External linksMol. Cell / PubMed:23317506
MethodsX-ray diffraction
Resolution2.54 - 2.99 Å
Structure data

PDB-4dx8:
ICAP1 in complex with KRIT1 N-terminus
Method: X-RAY DIFFRACTION / Resolution: 2.54 Å

PDB-4dx9:
ICAP1 in complex with integrin beta 1 cytoplasmic tail
Method: X-RAY DIFFRACTION / Resolution: 2.99 Å

Chemicals

ChemComp-BR:
BROMIDE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / Protein-protein complex / PTB domain / Nudix fold / Protein-protein interaction / Membrane / nucleus / Integrin binding / Integrin beta-1

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