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TitleStructure of the Tpr Domain of Aip: Lack of Client Protein Interaction with the C-Terminal Alpha-7 Helix of the Tpr Domain of Aip is Sufficient for Pituitary Adenoma Predisposition.
Journal, issue, pagesPlos One, Vol. 7, Page 53339-, Year 2012
Publish dateFeb 9, 2012 (structure data deposition date)
AuthorsMorgan, R.M. / Hernandez-Ramirez, L.C. / Trivellin, G. / Zhou, L. / Roe, S.M. / Korbonits, M. / Prodromou, C.
External linksPlos One / PubMed:23300914
MethodsX-ray diffraction
Resolution1.895 - 2.006 Å
Structure data

PDB-4aif:
AIP TPR domain in complex with human Hsp90 peptide
Method: X-RAY DIFFRACTION / Resolution: 2.006 Å

PDB-4apo:
AIP TPR domain in complex with human Tomm20 peptide
Method: X-RAY DIFFRACTION / Resolution: 1.895 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-12P:
DODECAETHYLENE GLYCOL / precipitant*YM

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN/PEPTIDE / SIGNALING PROTEIN-PEPTIDE COMPLEX / ARYL HYDROCARBON RECEPTOR

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