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Title | Piperidinols that Show Anti-Tubercular Activity as Inhibitors of Arylamine N-Acetyltransferase: An Essential Enzyme for Mycobacterial Survival Inside Macrophages. |
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Journal, issue, pages | Plos One, Vol. 7, Page 52790-, Year 2012 |
Publish date | Aug 2, 2012 (structure data deposition date) |
Authors | Abuhammad, A. / Fullam, E. / Lowe, E.D. / Staunton, D. / Kawamura, A. / Westwood, I.M. / Bhakta, S. / Garner, A.C. / Wilson, D.L. / Seden, P.T. ...Abuhammad, A. / Fullam, E. / Lowe, E.D. / Staunton, D. / Kawamura, A. / Westwood, I.M. / Bhakta, S. / Garner, A.C. / Wilson, D.L. / Seden, P.T. / Davies, S.G. / Russell, A.J. / Garman, E.F. / Sim, E. |
External links | Plos One / PubMed:23285185 |
Methods | X-ray diffraction |
Resolution | 2.7 Å |
Structure data | PDB-4b55: |
Chemicals | ChemComp-P18: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE / TUBERCULOSIS / COVALENT INHIBITOR |