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Structure paper

TitleStructural and functional insights into (s)-ureidoglycolate dehydrogenase, a metabolic branch point enzyme in nitrogen utilization.
Journal, issue, pagesPlos One, Vol. 7, Page e52066-e52066, Year 2012
Publish dateJun 12, 2012 (structure data deposition date)
AuthorsKim, M.I. / Shin, I. / Cho, S. / Lee, J. / Rhee, S.
External linksPlos One / PubMed:23284870
MethodsX-ray diffraction
Resolution1.64 - 2.13 Å
Structure data

PDB-4fjs:
Crystal structure of ureidoglycolate dehydrogenase enzyme in apo form
Method: X-RAY DIFFRACTION / Resolution: 2.13 Å

PDB-4fju:
Crystal structure of ureidoglycolate dehydrogenase in ternary complex with NADH and glyoxylate
Method: X-RAY DIFFRACTION / Resolution: 1.771 Å

PDB-4h8a:
Crystal structure of ureidoglycolate dehydrogenase in binary complex with NADH
Method: X-RAY DIFFRACTION / Resolution: 1.64 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-NAI:
1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE

ChemComp-GLV:
GLYOXYLIC ACID

Source
  • escherichia coli (E. coli)
KeywordsOXIDOREDUCTASE / ALLD / NAD(P)H-DEPENDENT OXIDOREDUCTASE / UREIDE PATHWAY / UREIDOGLYCOLATE / OXALURATE / ANTIPARALLEL BETA-SHEET FOLD / UREIDOGLYCOLATE DEHYDROGENASE / Rossmann Fold

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