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Structure paper

TitleStructural Basis of DNA Ligase IV-Artemis Interaction in Nonhomologous End-Joining.
Journal, issue, pagesCell Rep, Vol. 2, Page 1505-1512, Year 2012
Publish dateNov 1, 2012 (structure data deposition date)
AuthorsDe Ioannes, P. / Malu, S. / Cortes, P. / Aggarwal, A.K.
External linksCell Rep / PubMed:23219551
MethodsX-ray diffraction
Resolution2.2502 - 2.8068 Å
Structure data

PDB-4hto:
Crystal structure of the DBD domain of human DNA ligase IV Apo form
Method: X-RAY DIFFRACTION / Resolution: 2.8068 Å

PDB-4htp:
Crystal structure of the DBD domain of human DNA ligase IV bound to Artemis peptide
Method: X-RAY DIFFRACTION / Resolution: 2.2502 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLIGASE / DNA binding protein / Helical domain / DNA binding domain / LIGASE/HYDROLASE / DNA / artemis / LIGASE-HYDROLASE complex

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