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TitleBroad and potent neutralization of HIV-1 by a gp41-specific human antibody.
Journal, issue, pagesNature, Vol. 491, Page 406-412, Year 2012
Publish dateJul 19, 2012 (structure data deposition date)
AuthorsHuang, J. / Ofek, G. / Laub, L. / Louder, M.K. / Doria-Rose, N.A. / Longo, N.S. / Imamichi, H. / Bailer, R.T. / Chakrabarti, B. / Sharma, S.K. ...Huang, J. / Ofek, G. / Laub, L. / Louder, M.K. / Doria-Rose, N.A. / Longo, N.S. / Imamichi, H. / Bailer, R.T. / Chakrabarti, B. / Sharma, S.K. / Alam, S.M. / Wang, T. / Yang, Y. / Zhang, B. / Migueles, S.A. / Wyatt, R. / Haynes, B.F. / Kwong, P.D. / Mascola, J.R. / Connors, M.
External linksNature / PubMed:23151583
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-4g6f:
Crystal Structure of 10E8 Fab in Complex with an HIV-1 gp41 Peptide
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • human immunodeficiency virus 1
KeywordsIMMUNE SYSTEM / Immunoglobulin / MPER / Antibody

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