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TitleCrystal structure of the human PRMT5:MEP50 complex.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 109, Page 17960-17965, Year 2012
Publish dateAug 22, 2012 (structure data deposition date)
AuthorsAntonysamy, S. / Bonday, Z. / Campbell, R.M. / Doyle, B. / Druzina, Z. / Gheyi, T. / Han, B. / Jungheim, L.N. / Qian, Y. / Rauch, C. ...Antonysamy, S. / Bonday, Z. / Campbell, R.M. / Doyle, B. / Druzina, Z. / Gheyi, T. / Han, B. / Jungheim, L.N. / Qian, Y. / Rauch, C. / Russell, M. / Sauder, J.M. / Wasserman, S.R. / Weichert, K. / Willard, F.S. / Zhang, A. / Emtage, S.
External linksProc. Natl. Acad. Sci. USA / PubMed:23071334
MethodsX-ray diffraction
Resolution2.06 Å
Structure data

PDB-4gqb:
Crystal Structure of the human PRMT5:MEP50 Complex
Method: X-RAY DIFFRACTION / Resolution: 2.06 Å

Chemicals

ChemComp-0XU:
(2S,5S,6E)-2,5-diamino-6-[(3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxydihydrofuran-2(3H)-ylidene]hexanoic acid

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/PROTEIN BINDING / TIM BARREL / BETA-PROPELLER / METHYLTRANSFERASE / METHYLATION / TRANSFERASE-PROTEIN BINDING complex

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