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TitleAn unexpected binding mode for a Pol II CTD peptide phosphorylated at Ser7 in the active site of the CTD phosphatase Ssu72.
Journal, issue, pagesGenes Dev., Vol. 26, Page 2265-2270, Year 2012
Publish dateSep 13, 2012 (structure data deposition date)
AuthorsXiang, K. / Manley, J.L. / Tong, L.
External linksGenes Dev. / PubMed:23070812
MethodsX-ray diffraction
Resolution2 - 2.2 Å
Structure data

PDB-4h3h:
Crystal structure of a ternary complex of human symplekin NTD, human Ssu72 and a RNA poymerase II CTD peptide phosphorylated at SER-7
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-4h3k:
Crystal structure of a ternary complex of human symplekin NTD, human Ssu72 and a RNA polymerase II CTD peptide phosphorylated at Ser-2, Ser-5 and Ser-7
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / Heat repeat / phosphatase / RNA polymerase II

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