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TitleMolecular Basis for Genetic Resistance of Anopheles gambiae to Plasmodium: Structural Analysis of TEP1 Susceptible and Resistant Alleles.
Journal, issue, pagesPlos Pathog., Vol. 8, Page e1002958-e1002958, Year 2012
Publish dateJan 11, 2012 (structure data deposition date)
AuthorsLe, B.V. / Williams, M. / Logarajah, S. / Baxter, R.H.
External linksPlos Pathog. / PubMed:23055931
MethodsX-ray diffraction
Resolution2.7 - 3.7 Å
Structure data

PDB-4d94:
Crystal Structure of TEP1r
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-4lnv:
Crystal Structure of TEP1s
Method: X-RAY DIFFRACTION / Resolution: 3.7 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-CL:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • anopheles gambiae (African malaria mosquito)
KeywordsIMMUNE SYSTEM / Plasmodium refractory allele / full-length protein / thioester / macroglobulin domains / component of innate immune response by the opsinization and melanization of pathogens / innate immunity / LRIM1 and APL1C

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