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TitleStructural Basis for Promiscuity and Specificity During Candida Glabrata Invasion of Host Epithelia.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 109, Page 16864-, Year 2012
Publish dateJan 18, 2012 (structure data deposition date)
AuthorsMaestre-Reyna, M. / Diderrich, R. / Veelders, M.S. / Eulenburg, G. / Kalugin, V. / Bruckner, S. / Keller, P. / Rupp, S. / Mosch, H. / Essen, L.
External linksProc. Natl. Acad. Sci. USA / PubMed:23035251
MethodsX-ray diffraction
Resolution1.24 - 2.05 Å
Structure data

PDB-4af9:
Crystal Structure of Epithelial Adhesin 1 A domain (Epa1A) from Candida glabrata in complex with Galb1-3Glc
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-4afa:
Crystal Structure of subtype-switched Epithelial Adhesin 1 to 2 A domain (Epa1to2A) from Candida glabrata in complex with glycerol
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

PDB-4afb:
Crystal Structure of subtype-switched Epithelial Adhesin 1 to 3 A domain (Epa1to3A) from Candida glabrata in complex with glycerol
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-4afc:
Crystal Structure of subtype-switched Epithelial Adhesin 1 to 6 A domain (Epa1to6A) from Candida glabrata in complex with Galb1-3Glc
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

PDB-4asl:
Structure of Epa1A in complex with the T-antigen (Gal-b1-3- GalNAc)
Method: X-RAY DIFFRACTION / Resolution: 1.24 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

ChemComp-NA:
Unknown entry

Source
  • candida glabrata (fungus)
KeywordsCELL ADHESION / LECTIN / TISSUE INVASION / PATHOGENICITY

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