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Structure paper

TitleOptimization of a GCaMP calcium indicator for neural activity imaging.
Journal, issue, pagesJ. Neurosci., Vol. 32, Page 13819-13840, Year 2012
Publish dateJun 14, 2011 (structure data deposition date)
AuthorsAkerboom, J. / Chen, T.W. / Wardill, T.J. / Tian, L. / Marvin, J.S. / Mutlu, S. / Calderon, N.C. / Esposti, F. / Borghuis, B.G. / Sun, X.R. ...Akerboom, J. / Chen, T.W. / Wardill, T.J. / Tian, L. / Marvin, J.S. / Mutlu, S. / Calderon, N.C. / Esposti, F. / Borghuis, B.G. / Sun, X.R. / Gordus, A. / Orger, M.B. / Portugues, R. / Engert, F. / Macklin, J.J. / Filosa, A. / Aggarwal, A. / Kerr, R.A. / Takagi, R. / Kracun, S. / Shigetomi, E. / Khakh, B.S. / Baier, H. / Lagnado, L. / Wang, S.S. / Bargmann, C.I. / Kimmel, B.E. / Jayaraman, V. / Svoboda, K. / Kim, D.S. / Schreiter, E.R. / Looger, L.L.
External linksJ. Neurosci. / PubMed:23035093
MethodsX-ray diffraction
Resolution1.7 - 2.4 Å
Structure data

PDB-3sg2:
Crystal Structure of GCaMP2-T116V,D381Y
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-3sg3:
Crystal Structure of GCaMP3-D380Y
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-3sg4:
Crystal Structure of GCaMP3-D380Y, LP(linker 2)
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-3sg5:
Crystal Structure of Dimeric GCaMP3-D380Y, QP(linker 1), LP(linker 2)
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-3sg6:
Crystal Structure of Dimeric GCaMP2-LIA(linker 1)
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-3sg7:
Crystal Structure of GCaMP3-KF(linker 1)
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

Source
  • gallus gallus (chicken)
  • aequorea victoria (jellyfish)
  • rattus norvegicus (Norway rat)
KeywordsFLUORESCENT PROTEIN / calcium sensor

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