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Structure paper

TitleStructural basis of functional group activation by sulfotransferases in complex metabolic pathways.
Journal, issue, pagesAcs Chem. Biol., Vol. 7, Page 1994-2003, Year 2012
Publish dateJul 27, 2012 (structure data deposition date)
AuthorsMcCarthy, J.G. / Eisman, E.B. / Kulkarni, S. / Gerwick, L. / Gerwick, W.H. / Wipf, P. / Sherman, D.H. / Smith, J.L.
External linksAcs Chem. Biol. / PubMed:22991895
MethodsX-ray diffraction
Resolution1.62 - 2.15 Å
Structure data

PDB-4gbm:
Sulfotransferase Domain from the Curacin Biosynthetic Pathway
Method: X-RAY DIFFRACTION / Resolution: 1.62 Å

PDB-4gox:
Sulfotransferase Domain from the Synechococcus PCC 7002 Olefin Synthase
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-A3P:
ADENOSINE-3'-5'-DIPHOSPHATE

ChemComp-CL:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-P6G:
HEXAETHYLENE GLYCOL / precipitant*YM

ChemComp-HOH:
WATER

Source
  • moorea producta (bacteria)
  • synechococcus sp. (bacteria)
KeywordsTRANSFERASE / sulfotransferase / polyketide synthase / curacin / PAP / PAPS / olefin synthase / hydrocarbon / 3'phosphoadenosine-5'phosphosulfate

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