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TitleA Transition-State Interaction Shifts Nucleobase Ionization toward Neutrality To Facilitate Small Ribozyme Catalysis.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 134, Page 16933-16936, Year 2012
Publish dateJul 19, 2012 (structure data deposition date)
AuthorsLiberman, J.A. / Guo, M. / Jenkins, J.L. / Krucinska, J. / Chen, Y. / Carey, P.R. / Wedekind, J.E.
External linksJ. Am. Chem. Soc. / PubMed:22989273
MethodsX-ray diffraction
Resolution2.641 - 2.84 Å
Structure data

PDB-4g6p:
Minimal Hairpin Ribozyme in the Precatalytic State with A38P Variation
Method: X-RAY DIFFRACTION / Resolution: 2.641 Å

PDB-4g6r:
Minimal Hairpin Ribozyme in the Transition State with G8I Variation
Method: X-RAY DIFFRACTION / Resolution: 2.832 Å

PDB-4g6s:
Minimal Hairpin Ribozyme in the Transition State with A38P Variation
Method: X-RAY DIFFRACTION / Resolution: 2.84 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-NCO:
COBALT HEXAMMINE(III)

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

KeywordsRNA / Structure-activity relationship / Nucleic Acid Conformation

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