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Structure paper

TitleMolecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 109, Page 15229-15234, Year 2012
Publish dateMay 15, 2012 (structure data deposition date)
AuthorsBuck-Koehntop, B.A. / Stanfield, R.L. / Ekiert, D.C. / Martinez-Yamout, M.A. / Dyson, H.J. / Wilson, I.A. / Wright, P.E.
External linksProc. Natl. Acad. Sci. USA / PubMed:22949637
MethodsNMR (solution) / X-ray diffraction
Resolution2.4 - 2.8 Å
Structure data

PDB-2lt7:
Solution NMR structure of Kaiso zinc finger DNA binding domain in complex with Kaiso binding site DNA
Method: SOLUTION NMR

PDB-4f6m:
Crystal structure of Kaiso zinc finger DNA binding domain in complex with Kaiso binding site DNA
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-4f6n:
Crystal structure of Kaiso zinc finger DNA binding protein in complex with methylated CpG site DNA
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
KeywordsMETAL BINDING PROTEIN/DNA / zinc finger / double helix / METAL BINDING PROTEIN-DNA complex / DNA BINDING PROTEIN/DNA / protein-DNA complex / DNA binding / DNA / DNA BINDING PROTEIN-DNA complex

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