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TitleThe structure of Enterococcus faecalis thymidylate synthase provides clues about folate bacterial metabolism.
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 68, Page 1232-1241, Year 2012
Publish dateDec 2, 2011 (structure data deposition date)
AuthorsPozzi, C. / Ferrari, S. / Cortesi, D. / Luciani, R. / Stroud, R.M. / Catalano, A. / Costi, M.P. / Mangani, S.
External linksActa Crystallogr. ,Sect. D / PubMed:22948925
MethodsX-ray diffraction
Resolution2.07 Å
Structure data

PDB-3uwl:
Crystal structure of Enteroccocus faecalis thymidylate synthase (EfTS) in complex with 5-formyl tetrahydrofolate
Method: X-RAY DIFFRACTION / Resolution: 2.07 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-FFO:
N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • enterococcus faecalis (bacteria)
KeywordsTRANSFERASE / methyltransferase

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