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TitleCrystal Structures of Penicillin-Binding Protein 3 (PBP3) from Methicillin-Resistant Staphylococcus aureus in the Apo and Cefotaxime-Bound Forms.
Journal, issue, pagesJ. Mol. Biol., Vol. 423, Page 351-364, Year 2012
Publish dateApr 25, 2012 (structure data deposition date)
AuthorsYoshida, H. / Kawai, F. / Obayashi, E. / Akashi, S. / Roper, D.I. / Tame, J.R. / Park, S.Y.
External linksJ. Mol. Biol. / PubMed:22846910
MethodsX-ray diffraction
Resolution2.301 - 2.4 Å
Structure data

PDB-3vsk:
Crystal structure of penicillin-binding protein 3 (PBP3) from methicilin-resistant Staphylococcus aureus in the apo form.
Method: X-RAY DIFFRACTION / Resolution: 2.301 Å

PDB-3vsl:
Crystal structure of penicillin-binding protein 3 (PBP3) from methicilin-resistant Staphylococcus aureus in the cefotaxime bound form.
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-CEF:
CEFOTAXIME, C3' cleaved, open, bound form / antibiotic*YM

Source
  • staphylococcus aureus (bacteria)
KeywordsPENICILLIN-BINDING PROTEIN / penicillin-binding domain / Transpeptidase

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