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TitleStructural and Biochemical Characterization of Human Adenylosuccinate Lyase (ADSL) and the R303C ADSL Deficiency-Associated Mutation.
Journal, issue, pagesBiochemistry, Vol. 51, Page 6701-6713, Year 2012
Publish dateJun 1, 2012 (structure data deposition date)
AuthorsRay, S.P. / Deaton, M.K. / Capodagli, G.C. / Calkins, L.A. / Sawle, L. / Ghosh, K. / Patterson, D. / Pegan, S.D.
External linksBiochemistry / PubMed:22812634
MethodsX-ray diffraction
Resolution2.6 - 2.7 Å
Structure data

PDB-4ffx:
Structural and Biochemical Characterization of Human Adenylosuccinate Lyase (ADSL) and the R303C ADSL Deficiency Associated Mutation
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-4flc:
Structural and Biochemical Characterization of Human Adenylosuccinate Lyase (ADSL) and the R303C ADSL Deficiency Associated Mutation
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLYASE / PURINE BIOSYNTHESIS / DISEASE MUTATION / PURINE METABOLISM

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