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TitleStructural and biochemical consequences of disease-causing mutations in the ankyrin repeat domain of the human TRPV4 channel.
Journal, issue, pagesBiochemistry, Vol. 51, Page 6195-6206, Year 2012
Publish dateFeb 27, 2012 (structure data deposition date)
AuthorsInada, H. / Procko, E. / Sotomayor, M. / Gaudet, R.
External linksBiochemistry / PubMed:22702953
MethodsX-ray diffraction
Resolution2.85 - 2.95 Å
Structure data

PDB-4dx1:
Crystal structure of the human TRPV4 ankyrin repeat domain
Method: X-RAY DIFFRACTION / Resolution: 2.85 Å

PDB-4dx2:
Crystal structure of the human TRPV4 ankyrin repeat domain
Method: X-RAY DIFFRACTION / Resolution: 2.95 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-BGC:
beta-D-glucopyranose

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

Source
  • homo sapiens (human)
KeywordsTRANSPORT PROTEIN / Ankyrin Repeat / Ion Channel / Menbrane / Membrane

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