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-Structure paper
Title | Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutations. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 109, Page 10322-10327, Year 2012 |
Publish date | May 4, 2012 (structure data deposition date) |
Authors | Gilsbach, B.K. / Ho, F.Y. / Vetter, I.R. / van Haastert, P.J. / Wittinghofer, A. / Kortholt, A. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:22689969 |
Methods | X-ray diffraction |
Resolution | 1.8 - 2.3 Å |
Structure data | PDB-4f0f: PDB-4f0g: PDB-4f1m: PDB-4f1o: PDB-4f1t: |
Chemicals | ChemComp-ACP: ChemComp-HOH: ChemComp-BTB: ChemComp-MG: ChemComp-H52: |
Source |
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Keywords | TRANSFERASE / SIGNALING PROTEIN / Protein Kinase / LRRK2 / ROCO / Kinase / ATP-binding / Nucleotide-binding / Serine/threonine-protein kinase / Parkinson disease / Signaling Protein/INHIBITOR / Signaling Protein-INHIBITOR complex |