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Structure paper

TitleCrystal structure of a voltage-gated sodium channel in two potentially inactivated states.
Journal, issue, pagesNature, Vol. 486, Page 135-139, Year 2012
Publish dateApr 10, 2012 (structure data deposition date)
AuthorsPayandeh, J. / Gamal El-Din, T.M. / Scheuer, T. / Zheng, N. / Catterall, W.A.
External linksNature / PubMed:22678296
MethodsX-ray diffraction
Resolution3.21 Å
Structure data

PDB-4ekw:
Crystal structure of the NavAb voltage-gated sodium channel (wild-type, 3.2 A)
Method: X-RAY DIFFRACTION / Resolution: 3.21 Å

Chemicals

ChemComp-PX4:
1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE / DMPC, phospholipid*YM

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • arcobacter butzleri (bacteria)
KeywordsTRANSPORT PROTEIN / voltage-gated ion channel / tetrameric ion channel superfamily / voltage-gated sodium channel / membrane

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