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Structure paper

TitleCrystal Structure of the Mobile Metallo-Beta-Lactamase Aim-1 from Pseudomonas Aeruginosa: Insights Into Antibiotic Binding and the Role of Gln157
Journal, issue, pagesAntimicrob. Agents Chemother., Vol. 56, Page 4341-, Year 2012
Publish dateJun 6, 2012 (structure data deposition date)
AuthorsLeiros, H.-K.S. / Borra, P.S. / Brandsdal, B.O. / Edvardsen, K.S.W. / Spencer, J. / Walsh, T.R. / Samuelsen, O.
External linksAntimicrob. Agents Chemother. / PubMed:22664968
MethodsX-ray diffraction
Resolution1.4 - 1.8 Å
Structure data

PDB-4awy:
Crystal Structure of the Mobile Metallo-beta-Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the role of Gln157
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-4awz:
Crystal Structure of the Mobile Metallo-beta-Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the role of Gln157
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-4ax0:
Q157A mutant. Crystal Structure of the Mobile Metallo-beta-Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the role of Gln157
Method: X-RAY DIFFRACTION / Resolution: 1.74 Å

PDB-4ax1:
Q157N mutant. Crystal Structure of the Mobile Metallo-beta-Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the role of Gln157
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-ACT:
ACETATE ION

Source
  • pseudomonas aeruginosa (bacteria)
KeywordsHYDROLASE / ANTIBIOTIC RESISTANCE / ACQUIRED B3 / DRUG BINDING SITE / INTRAMOLECULAR DISULPHIDE BRIDGES

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