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TitleAtl1 Regulates Choice between Global Genome and Transcription-Coupled Repair of O(6)-Alkylguanines.
Journal, issue, pagesMol. Cell, Vol. 47, Page 50-60, Year 2012
Publish dateApr 13, 2012 (structure data deposition date)
AuthorsLatypov, V.F. / Tubbs, J.L. / Watson, A.J. / Marriott, A.S. / McGown, G. / Thorncroft, M. / Wilkinson, O.J. / Senthong, P. / Butt, A. / Arvai, A.S. ...Latypov, V.F. / Tubbs, J.L. / Watson, A.J. / Marriott, A.S. / McGown, G. / Thorncroft, M. / Wilkinson, O.J. / Senthong, P. / Butt, A. / Arvai, A.S. / Millington, C.L. / Povey, A.C. / Williams, D.M. / Santibanez-Koref, M.F. / Tainer, J.A. / Margison, G.P.
External linksMol. Cell / PubMed:22658721
MethodsX-ray diffraction
Resolution2.8402 - 3.0989 Å
Structure data

PDB-4enj:
Crystal structure of S. pombe Atl1 in complex with damaged DNA containing O6-hydroxyethylguanine
Method: X-RAY DIFFRACTION / Resolution: 3.0989 Å

PDB-4enk:
Crystal structure of S. pombe Atl1 in complex with damaged DNA containing O6-propylguanine
Method: X-RAY DIFFRACTION / Resolution: 3.0445 Å

PDB-4enm:
Crystal structure of S. pombe Atl1 in complex with damaged DNA containing O6-benzylguanine
Method: X-RAY DIFFRACTION / Resolution: 2.8402 Å

PDB-4enn:
Crystal structure of S. pombe Atl1 in complex with damaged DNA containing O6-carboxymethylguanine
Method: X-RAY DIFFRACTION / Resolution: 2.8448 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • schizosaccharomyces pombe (fission yeast)
  • synthetic construct (others)
  • schizosaccharomyces pombe 972h- (yeast)
KeywordsDNA BINDING PROTEIN/DNA / Alkyltransferase / DNA repair / nucleotide excision repair / NER / base repair / DNA / DNA Damage / Guanine / Alkylation / DNA BINDING PROTEIN-DNA complex

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