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TitleGeneration, Characterization and Structural Data of Chymase Binding Proteins Based on the Human Fyn Kinase SH3 Domain.
Journal, issue, pagesMabs, Vol. 4, Page 497-, Year 2012
Publish dateJan 23, 2012 (structure data deposition date)
AuthorsSchlatter, D. / Brack, S. / Banner, D.W. / Batey, S. / Benz, J. / Bertschinger, J. / Huber, W. / Joseph, C. / Rufer, A. / Van Der Klooster, A. ...Schlatter, D. / Brack, S. / Banner, D.W. / Batey, S. / Benz, J. / Bertschinger, J. / Huber, W. / Joseph, C. / Rufer, A. / Van Der Klooster, A. / Weber, M. / Grabulovski, D. / Hennig, M.
External linksMabs / PubMed:22653218
MethodsX-ray diffraction
Resolution1.4 - 2.25 Å
Structure data

PDB-4afq:
Human Chymase - Fynomer Complex
Method: X-RAY DIFFRACTION / Resolution: 1.51 Å

PDB-4afs:
Human Chymase - Fynomer Complex
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-4afu:
Human Chymase - Fynomer Complex
Method: X-RAY DIFFRACTION / Resolution: 1.82 Å

PDB-4afz:
Human Chymase - Fynomer Complex
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-4ag1:
Human Chymase - Fynomer Complex
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

PDB-4ag2:
Human Chymase - Fynomer Complex
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-FLC:
CITRATE ANION

ChemComp-CPS:
3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE / detergent*YM

ChemComp-HOH:
WATER

ChemComp-ZN:
Unknown entry

ChemComp-PO4:
PHOSPHATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-TAR:
D(-)-TARTARIC ACID

ChemComp-SO4:
SULFATE ION

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

ChemComp-LMR:
(2S)-2-hydroxybutanedioic acid

ChemComp-NA:
Unknown entry

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsHYDROLASE/DE NOVO PROTEIN / HYDROLASE-DE NOVO PROTEIN COMPLEX / INHIBITOR / SERINE PROTEASE

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