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TitleStructural Insights into Human Peroxisome Proliferator Activated Receptor Delta (PPAR-Delta) Selective Ligand Binding.
Journal, issue, pagesPlos One, Vol. 7, Page e33643-e33643, Year 2012
Publish dateAug 27, 2011 (structure data deposition date)
AuthorsBatista, F.A. / Trivella, D.B. / Bernardes, A. / Gratieri, J. / Oliveira, P.S. / Figueira, A.C. / Webb, P. / Polikarpov, I.
External linksPlos One / PubMed:22606221
MethodsX-ray diffraction
Resolution1.953 Å
Structure data

PDB-3tkm:
Crystal structure PPAR delta binding GW0742
Method: X-RAY DIFFRACTION / Resolution: 1.953 Å

Chemicals

ChemComp-GW0:
{4-[({2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl}methyl)sulfanyl]-2-methylphenoxy}acetic acid / agonist*YM

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION/TRANSCRIPTION ACTIVATOR / nuclear receptor / TRANSCRIPTION / TRANSCRIPTION-TRANSCRIPTION ACTIVATOR complex

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