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TitleThiamin pyrimidine biosynthesis in Candida albicans : a remarkable reaction between histidine and pyridoxal phosphate.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 134, Page 9157-9159, Year 2012
Publish dateApr 23, 2012 (structure data deposition date)
AuthorsLai, R.Y. / Huang, S. / Fenwick, M.K. / Hazra, A. / Zhang, Y. / Rajashankar, K. / Philmus, B. / Kinsland, C. / Sanders, J.M. / Ealick, S.E. / Begley, T.P.
External linksJ. Am. Chem. Soc. / PubMed:22568620
MethodsX-ray diffraction
Resolution1.6 - 2.2 Å
Structure data

PDB-4esw:
Crystal structure of C. albicans Thi5 H66G mutant
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-4esx:
Crystal structure of C. albicans Thi5 complexed with PLP
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-CIT:
CITRIC ACID

ChemComp-HOH:
WATER

Source
  • candida albicans (yeast)
KeywordsTRANSFERASE / Thiamin pyrimidine biosynthesis

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