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Structure paper

TitleCrystal Structure of a Trypanosoma Brucei Metacaspase.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 109, Page 7469-, Year 2012
Publish dateJan 18, 2012 (structure data deposition date)
AuthorsMcluskey, K. / Rudolf, J. / Proto, W.R. / Isaacs, N.W. / Coombs, G.H. / Moss, C.X. / Mottram, J.C.
External linksProc. Natl. Acad. Sci. USA / PubMed:22529389
MethodsX-ray diffraction
Resolution1.4 - 2.1 Å
Structure data

PDB-4af8:
The structural basis for metacaspase substrate specificity and activation
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

PDB-4afp:
The structure of metacaspase 2 from T. brucei determined in the presence of Samarium
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-4afr:
THE STRUCTURE OF METACASPASE 2 (C213A MUTANT) FROM T. BRUCEI
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-4afv:
THE STRUCTURE OF METACASPASE 2 FROM T. BRUCEI DETERMINED IN THE PRESENCE OF CALCIUM CHLORIDE
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-SM:
SAMARIUM (III) ION

Source
  • trypanosoma brucei (eukaryote)
  • trypanosoma brucei brucei (eukaryote)
KeywordsHYDROLASE / CYSTEINE PEPTIDASE / CASPASE/HEMOGLOBIN FOLD

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