Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Metal-directed, chemically tunable assembly of one-, two- and three-dimensional crystalline protein arrays.
Journal, issue, pages	Nat Chem, Vol. 4, Issue 5, Page 375-382, Year 2012
Publish date	Mar 4, 2012
Authors	Jeffrey D Brodin / X I Ambroggio / Chunyan Tang / Kristin N Parent / Timothy S Baker / F Akif Tezcan /
PubMed Abstract	Proteins represent the most sophisticated building blocks available to an organism and to the laboratory chemist. Yet, in contrast to nearly all other types of molecular building blocks, the designed ...Proteins represent the most sophisticated building blocks available to an organism and to the laboratory chemist. Yet, in contrast to nearly all other types of molecular building blocks, the designed self-assembly of proteins has largely been inaccessible because of the chemical and structural heterogeneity of protein surfaces. To circumvent the challenge of programming extensive non-covalent interactions to control protein self-assembly, we have previously exploited the directionality and strength of metal coordination interactions to guide the formation of closed, homoligomeric protein assemblies. Here, we extend this strategy to the generation of periodic protein arrays. We show that a monomeric protein with properly oriented coordination motifs on its surface can arrange, on metal binding, into one-dimensional nanotubes and two- or three-dimensional crystalline arrays with dimensions that collectively span nearly the entire nano- and micrometre scale. The assembly of these arrays is tuned predictably by external stimuli, such as metal concentration and pH.
External links	Nat Chem / PubMed:22522257 / PubMed Central
Methods	EM (helical sym.) / X-ray diffraction
Resolution	2 - 10.0 Å
Structure data	EMDB-5341: Chemically controlled assembly of 1, 2 and 3-dimensional protein arrays Method: EM (helical sym.) / Resolution: 10.0 Å PDB-3tol: Crystal structure of an engineered cytochrome cb562 that forms 1D, Zn-mediated coordination polymers Method: X-RAY DIFFRACTION / Resolution: 2 Å PDB-3tom: Crystal structure of an engineered cytochrome cb562 that forms 2D, Zn-mediated sheets Method: X-RAY DIFFRACTION / Resolution: 2.3 Å
Chemicals	ChemComp-HEM: PROTOPORPHYRIN IX CONTAINING FE ChemComp-ZN: Unknown entry ChemComp-CA: Unknown entry ChemComp-HOH: WATER
Source	escherichia coli (E. coli)
Keywords	METAL BINDING PROTEIN / four helix bundle / electron transfer / periplasmic space