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Structure paper

TitleStructural Insights into TIR Domain Specificity of the Bridging Adaptor Mal in TLR4 Signaling
Journal, issue, pagesPlos One, Vol. 7, Page e34202-e34202, Year 2012
Publish dateOct 23, 2011 (structure data deposition date)
AuthorsLin, Z. / Lu, J. / Zhou, W. / Shen, Y.
External linksPlos One / PubMed:22485159
MethodsX-ray diffraction
Resolution2.4 - 3.1 Å
Structure data

PDB-3ub2:
TIR domain of Mal/TIRAP
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-3ub3:
D96N variant of TIR domain of Mal/TIRAP
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

PDB-3ub4:
S180L variant of TIR domain of Mal/TIRAP
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Chemicals

ChemComp-DTT:
2,3-DIHYDROXY-1,4-DITHIOBUTANE

ChemComp-HOH:
WATER

ChemComp-DTV:
(2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / TIR domain / TLRs adaptor

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