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TitleStructure-based redesign of GST A2-2 for enhanced catalytic efficiency with azathioprine.
Journal, issue, pagesChem. Biol., Vol. 19, Page 414-421, Year 2012
Publish dateDec 19, 2011 (structure data deposition date)
AuthorsZhang, W. / Moden, O. / Tars, K. / Mannervik, B.
External linksChem. Biol. / PubMed:22444596
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-4acs:
Crystal structure of mutant GST A2-2 with enhanced catalytic efficiency with azathioprine
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-GSH:
GLUTATHIONE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / OXIDATION-REDUCTION

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