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Structure paper

TitleThe Structure of the Asap Core Complex Reveals the Existence of a Pinin-Containing Psap Complex
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 19, Page 378-, Year 2012
Publish dateNov 8, 2011 (structure data deposition date)
AuthorsMurachelli, A.G. / Ebert, J. / Basquin, C. / Le Hir, H. / Conti, E.
External linksNat. Struct. Mol. Biol. / PubMed:22388736
MethodsX-ray diffraction
Resolution1.5 - 1.9 Å
Structure data

PDB-4a6q:
Crystal structure of mouse SAP18 residues 6-143
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-4a8x:
Structure of the core ASAP complex
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-4a90:
Crystal structure of mouse SAP18 residues 1-143
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-IPA:
ISOPROPYL ALCOHOL / alkaloid*YM

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
  • drosophila melanogaster (fruit fly)
KeywordsTRANSCRIPTION / SPLICING / RNA METABOLISM / UBIQUITIN-LIKE / RNA PROCESSING / NONSENSE MEDIATED DECAY / NMD / HDAC / HISTONE DEACETYLATION

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