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TitleHigh abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions
Journal, issue, pagesNat. Med., Vol. 18, Page 441-445, Year 2012
Publish dateMar 16, 2016 (structure data deposition date)
AuthorsDi Niro, R. / Mesin, L. / Zheng, N.Y. / Stamnaes, J. / Morrissey, M. / Lee, J.H. / Huang, M. / Iversen, R. / du Pre, M.F. / Qiao, S.W. ...Di Niro, R. / Mesin, L. / Zheng, N.Y. / Stamnaes, J. / Morrissey, M. / Lee, J.H. / Huang, M. / Iversen, R. / du Pre, M.F. / Qiao, S.W. / Lundin, K.E. / Wilson, P.C. / Sollid, L.M.
External linksNat. Med. / PubMed:22366952
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-5it2:
Structure of a transglutaminase 2-specific autoantibody 693-10-B06 Fab fragment
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Transglutaminase 2 / autoantibody / Fab fragment

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